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It is most useful when a conventional treatment path has been followed appropriately and has plateaued

No alternative cause, such as medication, depression, or relationship issues

doi:10.1089/acm.2011.0503, PMID: 22757691 Ding W, Liu Y (2011) Genistein attenuates genioglossus muscle fatigue under chronic intermittent hypoxia by down-regulation of oxidative stress level and up-regulation of antioxidant enzyme activity through ERK1/2 signaling pathway

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